Can I take Naproxen bp and Paracetamol together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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It is generally safe to take naproxen and paracetamol together. There is no direct interaction between these two medicines. In fact, doctors often recommend taking them together for short periods if one medicine alone is not providing enough pain relief.
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Why this happens
Naproxen and paracetamol work in different ways to block pain signals. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation, while paracetamol works mainly in the central nervous system. Because they do not interfere with how the body processes (metabolises) each other, they can be used at the same time.
What you should do
You can take these medicines together, but ensure you do not exceed the maximum daily dose for either. Always take naproxen with food or a milky drink to protect your stomach. If you find you need to take this combination for more than a few days, speak to your pharmacist or GP to ensure there isn't an underlying issue that needs different treatment.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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