Can I take Losartin and Metformin together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking losartan and metformin together is generally safe, but it may slightly increase the risk of your blood sugar levels dropping too low (hypoglycaemia). Additionally, both drugs can affect your kidney function, especially if you become dehydrated.
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Why this happens
Losartan can improve how your body responds to insulin, which may enhance the blood-sugar-lowering effect of metformin. Both medications are also processed or cleared through the kidneys, and their combined effect can occasionally put extra strain on kidney function.
What you should do
You can take these medicines together, but you should monitor your blood sugar levels more closely when starting or changing doses. Be sure to stay well-hydrated. If you feel dizzy, shaky, or unusually tired, check your blood sugar. Attend your regular blood tests to monitor your kidney function as requested by your doctor.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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