Can I take Prozac and Vitamin d together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known harmful interaction between Prozac (fluoxetine) and Vitamin D. It is generally considered safe to take these two together.
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Why this happens
Prozac is an antidepressant (SSRI) processed by specific liver enzymes, while Vitamin D is a fat-soluble vitamin processed differently by the body. They do not interfere with each other's absorption, metabolism, or effectiveness.
What you should do
You can continue taking both as prescribed. It is always a good idea to inform your doctor or pharmacist about all supplements you are taking, but no special precautions are needed for this combination.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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