Can I take Magnesium and Wegovy flextouch together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
There is no known direct interaction between magnesium supplements and Wegovy (semaglutide). However, both can affect your digestive system. Wegovy slows down how quickly your stomach empties, which could theoretically change how quickly your body absorbs magnesium, though this is rarely a clinical concern. Additionally, both can cause side effects like nausea or changes in bowel habits (magnesium often softens stools, while Wegovy can cause constipation or diarrhoea).
In this article:
Continue reading below
Why this happens
Wegovy is a GLP-1 receptor agonist that delays 'gastric emptying' (the speed at which food and pills leave the stomach). This can alter the timing of absorption for oral supplements like magnesium. There are no shared metabolic pathways or conflicting chemical actions between the two.
What you should do
It is generally safe to take magnesium while using Wegovy. To ensure the best absorption and to avoid any potential stomach upset, you may wish to take your magnesium supplement at a different time of day than when you experience the most side effects from your Wegovy injection. If you experience severe diarrhoea or stomach pain, consult your doctor.
Continue reading below
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions
Treatment and medication
Can I take Ramipril and Ibuprofen together?
Taking ibuprofen while on ramipril can make your blood pressure medication less effective. More importantly, it can significantly increase the risk of kidney problems and may cause your body to hold onto too much potassium.
Treatment and medication
Can I take Maitake and Shiitake together?
Taking maitake and shiitake mushrooms together may increase the risk of bruising or bleeding. Both mushrooms contain natural compounds that can thin the blood and slow down the clotting process. While they are commonly eaten together in food, taking them in concentrated supplement form increases this effect.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.
Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.