Can I take Ibuprofen gel 10% and Lactulose together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There is no known interaction between ibuprofen gel and lactulose. It is safe to use these two medications together.
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Why this happens
Ibuprofen gel is applied to the skin and acts locally; very little of the medicine enters the bloodstream. Lactulose is a sugar-based laxative that stays mostly in the bowel to soften stools. Because they work in completely different parts of the body and are processed differently, they do not interfere with one another.
What you should do
You can continue to use both medications as directed by your doctor or the product packaging. Always ensure you wash your hands after applying ibuprofen gel to avoid accidental contact with your eyes or mouth.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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