Can I take Clopidogrel and Fenofibrate together?
Drug interaction guide
Originally published 25 Jan 2026
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Taking clopidogrel and fenofibrate together may slightly increase the risk of bleeding or bruising. While this combination is often prescribed together for heart health, it requires careful monitoring.
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Why this happens
Both medications can affect how your blood clots. Clopidogrel stops platelets from sticking together, while fenofibrate can sometimes increase the effects of blood-thinning processes in the body. Additionally, fenofibrate may slightly interfere with the enzymes in the liver that activate clopidogrel, though this effect is generally considered small.
What you should do
You can usually take these medicines together, but you should be alert for any unusual signs. Contact your doctor if you notice unexplained bruising, nosebleeds, blood in your urine or stools, or if a small cut takes a very long time to stop bleeding. Do not stop taking either medication without consulting your healthcare provider.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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