Can I take Atorvastatin and Flecainide together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There is no known direct interaction between atorvastatin and flecainide. Both medications can be taken together safely in most cases.
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Why this happens
Atorvastatin and flecainide are processed by different pathways in the liver. Atorvastatin is primarily broken down by an enzyme called CYP3A4, while flecainide is handled by CYP2D6. Because they use different 'routes', they do not interfere with each other's levels in the blood.
What you should do
You can continue taking both medications as prescribed by your doctor. However, always inform your healthcare provider if you experience unusual muscle pain (a potential side effect of statins) or changes in your heart rhythm, as these medications are treating your heart health and cholesterol levels.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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