Can I take Anastrozole and Omeprazole together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
There is no known interaction between anastrozole and omeprazole. It is generally considered safe to take these two medications together.
In this article:
Continue reading below
Why this happens
Anastrozole does not require a specific stomach acid level to be absorbed properly, so the acid-reducing effects of omeprazole do not interfere with it. Furthermore, these drugs are processed by different pathways in the liver, meaning they do not compete with or affect each other's metabolism.
What you should do
You can continue to take both medications as prescribed by your doctor. You do not need to space them apart or change the time of day you take them. Always inform your healthcare team if you start any new supplements or over-the-counter medicines.
Continue reading below
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Paracetamol and Ibuprofen together?
There is no harmful interaction between paracetamol and ibuprofen. In fact, they are often taken together because they work in different ways to provide better pain relief than either medicine alone.

Treatment and medication
Can I take Levothyroxine and Coffee together?
Drinking coffee at the same time as taking levothyroxine can significantly reduce the amount of medicine your body absorbs. This means your thyroid hormone levels may stay too low, and your symptoms (like tiredness or feeling cold) might not improve as they should.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.