Can I take Amlodopine and Citalopram together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
Taking amlodipine and citalopram together may increase the risk of developing an abnormal heart rhythm. While both are commonly prescribed together, they can both affect the electrical activity of your heart. In rare cases, this can lead to a serious condition called QT prolongation, where the heart muscle takes longer than normal to recharge between beats. This can cause palpitations, dizziness, or fainting.
In this article:
Continue reading below
Why this happens
Both medications have the potential to affect the 'QT interval' (the electrical timing of the heart). Citalopram is known to cause this effect, especially at higher doses, and amlodipine may occasionally contribute to this or change how the heart responds to electrical signals.
What you should do
For most people, this combination is safe, but you should use caution. Ensure your doctor knows you are taking both. Seek medical help immediately if you feel a sudden fast or pounding heartbeat, severe dizziness, or if you faint. Your doctor may occasionally want to check your heart rhythm with an ECG (heart trace) or monitor your salt levels (electrolytes) through blood tests.
Continue reading below
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Lions mane and Maitake together?
Both Lion's Mane and Maitake mushrooms may lower blood sugar levels and slow down blood clotting. Taking them together might increase the risk of your blood sugar dropping too low (hypoglycaemia) or increase the chance of bruising and bleeding.

Treatment and medication
Can I take Amitriptyline and Zopiclone together?
Taking amitriptyline and zopiclone together can make you feel extremely drowsy, dizzy, and confused. It significantly increases the risk of falling over, especially in the dark or when getting out of bed at night. It can also cause your breathing to become very slow or shallow, and may lead to severe coordination problems.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.