Can I take Amlodipine/ valsartan and Nebivolol together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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Taking these medicines together can cause your blood pressure to drop lower than intended. It may also slow your heart rate more than usual. This can make you feel dizzy, lightheaded, or faint, especially when standing up quickly.
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Why this happens
All three medicines work to lower blood pressure but in different ways. Amlodipine relaxes blood vessels, valsartan blocks a hormone that narrows vessels, and nebivolol slows the heart rate. When combined, their effects add together (additive effect).
What you should do
Use with caution. Your doctor has likely prescribed this combination intentionally, but you should monitor your blood pressure and heart rate regularly. If you feel very dizzy, tired, or notice a very slow pulse, contact your doctor. To avoid dizziness, stand up slowly from a sitting or lying position.
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Important precautions
Asthma or COPD
Do not take this medicine if you have asthma, a history of wheezing, or severe chronic obstructive pulmonary disease (COPD), as it can cause life-threatening narrowing of the airways.
Food and drink warnings
Alcohol
Drinking alcohol can increase the blood-pressure-lowering effect of these medicines, which may make you feel dizzy, lightheaded, or faint, especially when standing up. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you first.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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