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Penne with Tomato Prosciutto Sauce

This penne with tomato prosciutto sauce is a sophisticated yet comforting high-protein meal that elevates simple store-cupboard staples. By slowly simmering Italian plum tomatoes with salty, crisped prosciutto and sweet red onions, you create a rich and savoury ragù with a wonderful depth of flavour. The secret to this dish lies in the resting time, which allows the various ingredients to meld together into a balanced, silky sauce that clings perfectly to the ridges of the penne rigate.

Ideal for a weekend dinner or a nutritious midweek feast, this homemade pasta dish provides a generous boost of protein thanks to the quality cured ham. Serve it in large bowls with plenty of shaved Parmigiano-Reggiano and perhaps a crisp green salad on the side. It is a brilliant example of how patient, slow cooking can transform a few high-quality ingredients into a truly restaurant-standard Italian meal.

Continue reading below

Ingredients for Penne with Tomato Prosciutto Sauce

  • 2 tablespoons olive oil

  • 1 large red onion, finely chopped (300g )

  • 2 garlic cloves, finely chopped

  • 170g thinly sliced fine-quality prosciutto, such as Prosciutto di Parma, finely chopped and separated into pieces (350ml )

  • 2 (800g) cans Italian plum tomatoes in juice, drained, reserving juice, and finely chopped

  • 1 teaspoon sugar

  • 450g penne rigate

  • Accompaniment: Parmigiano-Reggiano (shavings or finely grated )

How to make Penne with Tomato Prosciutto Sauce

Heat oil in a wide heavy medium pot over medium-high heat until it shimmers, then sauté onion until golden, about 10 minutes. Add garlic and sauté until golden, about 1 minute. Add prosciutto and sauté until golden, about 4 minutes. Add tomatoes with reserved juice, sugar, and 1/4 teaspoons each of salt and pepper and simmer, uncovered, stirring occasionally, until thickened, 45 minutes to 1 hour. Cool, uncovered, then chill, covered, at least 8 hours (to allow flavours to develop).

Cook penne in a pasta pot of boiling salted water (3 tablespoons salt for 5.7L water) until al dente. Drain well.

While pasta cooks, reheat sauce over medium heat.

Toss pasta with some of sauce in a serving bowl and serve remaining sauce on the side.

Disclaimer

While every effort has been made to ensure the information is accurate and up to date, individual needs may vary and dietary requirements can differ based on personal health conditions. Always check food labels and allergen information before preparing or consuming any recipe. If you have specific health concerns, allergies, intolerances, or are following a medically prescribed diet, seek advice from your GP, pharmacist, or a registered dietitian before making significant changes to your diet or lifestyle.

Article history

The information on this page is peer reviewed by qualified clinicians.

  • 17 Jan 2026 | Originally published

    Authored by:

    UK recipe editors

    Peer reviewed by

    UK recipe editors
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