Can I take Mirabegron astellas and Rivaroxaban together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
There is no known direct interaction between mirabegron and rivaroxaban. It is generally considered safe to take these two medications together.
In this article:
Continue reading below
Why this happens
Mirabegron and rivaroxaban are processed by different pathways in the body. Mirabegron is primarily broken down by enzymes called CYP3A4 and CYP2D6, while rivaroxaban is processed by CYP3A4 and a transport protein called P-gp. While they share the CYP3A4 pathway, studies show that mirabegron does not significantly change the levels of drugs like rivaroxaban in the blood.
What you should do
You can take both medications as prescribed by your doctor. However, always monitor for any unusual side effects, such as unexpected bruising or bleeding (related to rivaroxaban) or a very fast heartbeat (related to mirabegron). If you notice anything unusual, contact your GP or pharmacist.
Continue reading below
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Esomeprazole and Trazodone together?
Esomeprazole may reduce the amount of trazodone that your body absorbs. This could potentially make trazodone less effective at treating your symptoms (such as depression or sleep issues). Additionally, both medications can rarely affect the electrical activity of your heart, though this risk is generally low.

Treatment and medication
Can I take Lions mane and Maitake together?
Both Lion's Mane and Maitake mushrooms may lower blood sugar levels and slow down blood clotting. Taking them together might increase the risk of your blood sugar dropping too low (hypoglycaemia) or increase the chance of bruising and bleeding.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.