Can I take Magnesium and Vitamin b2 together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known negative interaction between magnesium and vitamin B2 (riboflavin). In fact, they are often taken together because they work well as a team in the body.
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Why this happens
Magnesium and vitamin B2 do not interfere with each other's absorption or metabolism. Instead, they have a 'synergistic' effect, meaning they help each other work. For example, magnesium is required for the body to properly use certain vitamins, and both are involved in the same energy-production processes within your cells.
What you should do
It is safe to take these two supplements together. They are frequently combined in a single tablet, particularly for people trying to prevent migraines. As with any supplement, stick to the recommended daily dose on the packaging unless your doctor tells you otherwise.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

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