Can I take Indapamide and Vitamin c together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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There is no known significant interaction between indapamide and vitamin C (ascorbic acid). It is generally considered safe to take these two together.
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Why this happens
Indapamide is a diuretic (water tablet) used to lower blood pressure, while vitamin C is a water-soluble vitamin. They are processed by the body through different pathways and do not interfere with each other's absorption, metabolism, or effectiveness.
What you should do
You can continue to take both as prescribed or recommended. As with any supplement, it is best to stick to the recommended daily allowance of vitamin C unless your doctor has advised otherwise.
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Important precautions
Sulphonamide allergy
Do not take indapamide if you have a known allergy to sulphonamide medicines (such as certain antibiotics), as you may have a similar allergic reaction to this medicine.
Low potassium (hypokalaemia)
Indapamide can significantly lower your blood potassium levels. You must have regular blood tests to monitor this, especially if you experience muscle weakness, cramps, or an irregular heartbeat.
Kidney stones (oxalate)
High doses of Vitamin C can increase the risk of developing kidney stones. Avoid supplements if you have a history of calcium oxalate stones or severe kidney disease.
Food and drink warnings
Alcohol
Drinking alcohol while taking indapamide can increase the blood-pressure-lowering effect of the medicine. This may make you feel dizzy, lightheaded, or faint, especially when standing up quickly. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you before drinking.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Treatment and medication
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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