Can I take Hard and Lansoprazole together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
There is no known interaction between 'hard' (assuming this refers to water hardness/calcium carbonate or general food) and lansoprazole. However, if 'hard' refers to 'hard liquor' (alcohol), it can irritate the stomach.
In this article:
Continue reading below
Why this happens
Lansoprazole reduces stomach acid. Alcohol can increase acid production and irritate the stomach lining, which may counteract the benefits of the medication.
What you should do
You can take lansoprazole with or without food. If you meant alcohol, it is best to limit intake as it can make your stomach symptoms worse. If 'hard' refers to something else, please clarify.
Continue reading below
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Ibuprofen and Naproxen together?
Taking ibuprofen and naproxen together significantly increases your risk of serious side effects, particularly stomach ulcers, internal bleeding, and kidney problems. It can also make your blood pressure rise and cause fluid retention.

Treatment and medication
Can I take Ramipril and Ibuprofen together?
Taking ibuprofen while on ramipril can make your blood pressure medication less effective. More importantly, it can significantly increase the risk of kidney problems and may cause your body to hold onto too much potassium.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.