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Can I take Ciprofloxacin and Dairy together?

Drug interaction guide

Taking ciprofloxacin at the same time as dairy products (like milk, cheese, or yoghurt) can significantly reduce the amount of medicine that gets into your bloodstream. This means the antibiotic may not work properly to clear your infection.

You should not take ciprofloxacin at the same time as having dairy because it can make the medicine less effective.

The calcium found in dairy products binds to the ciprofloxacin in your stomach, forming a large 'clump' that the body cannot absorb. This is known as chelation.

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How to know if you are having a drug interaction

You may be experiencing an interaction between ciprofloxacin and dairy if:

  • Your infection isn’t improving as expected.

  • You still have symptoms like fever, pain, or swelling after a few days of treatment.

  • You notice the medicine isn’t working as well as usual.

These can be signs that the antibiotic isn’t being fully absorbed.

What you should do

If you notice any of the above symptoms, you should:

  • Contact your doctor or pharmacist - don’t stop the antibiotic on your own.

  • Check how you took the medicine and avoid taking it with dairy next time.

  • Follow your prescribed course carefully to make sure the infection is properly treated.

  • Report any persistent symptoms so your doctor can decide if a different treatment is needed.

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Important precautions

Dairy consumption (milk, cheese, yoghurt) and calcium-fortified juices

  • Do not take ciprofloxacin at the same time as dairy products or calcium-fortified drinks. These significantly reduce the amount of medicine absorbed by your body.

  • Take ciprofloxacin at least 2 hours before or 4 hours after consuming these products.

  • You can still eat meals containing dairy, but avoid drinking large glasses of milk or eating large amounts of yoghurt/cheese around the time you take your dose.

Tendonitis or tendon rupture

Stop taking this medicine and seek immediate medical help if you experience pain, swelling, or inflammation in any tendon (such as the ankle or wrist).

Ciprofloxacin increases the risk of tendon rupture, even after the course is finished.

Sunlight exposure (Photosensitivity)

This medicine makes your skin much more sensitive to sunlight. Avoid bright sunlight and do not use sunbeds; use a high-factor sun cream even on cloudy days to prevent severe skin reactions.

Food and drink warnings

Caffeine (coffee, tea, cola, energy drinks)

Ciprofloxacin can stop your body from breaking down caffeine as quickly as usual. This can lead to a build-up of caffeine in your system, making you feel shaky, restless, or causing a racing heartbeat and insomnia.

It is best to limit your caffeine intake while taking this medicine.

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Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.

Article history

The information on this page is written and peer reviewed by qualified clinicians.

  • 25 Jan 2026 | Originally published
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