Can I take Atorvastatin and Isosorbide mononitrate/carmil/monomil together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
There is no known direct interaction between atorvastatin and isosorbide mononitrate (also known by brand names like Monomil). These two medicines are frequently prescribed together for heart health.
In this article:
Continue reading below
Why this happens
Atorvastatin works in the liver to lower cholesterol, while isosorbide mononitrate works by relaxing blood vessels to improve blood flow. They are processed by different pathways in the body and do not interfere with each other's effectiveness or safety.
What you should do
You can safely take these medicines together as prescribed by your doctor. Always ensure you attend your regular blood tests to monitor your cholesterol levels and liver function while taking a statin.
Continue reading below
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Allupurinol and Atenolol together?
There is a potential for these two medicines to interact, which may lead to an increased risk of allergic reactions or a slight change in how your kidneys handle the medication. While most people take this combination without issues, there have been rare reports of serious skin rashes or hypersensitivity reactions when taking allopurinol alongside certain blood pressure medications like atenolol.

Treatment and medication
Can I take Co-codamol and Ibuprofen together?
It is safe to take co-codamol and ibuprofen together. They are different types of painkillers that work in different ways to provide better pain relief than taking either one alone.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.