Can I take Apixaban and Bisoprolol together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
- DownloadDownload
- Share
- Language
- Discussion
There is no direct interaction between apixaban and bisoprolol. They work in different ways and do not interfere with how the body processes each other.
In this article:
Continue reading below
Why this happens
Apixaban is an anticoagulant (blood thinner) that works by blocking a clotting factor called Factor Xa. Bisoprolol is a beta-blocker that slows the heart rate and lowers blood pressure. They are processed by different pathways in the liver and kidneys, and their primary effects do not overlap in a way that causes harm.
What you should do
You can safely take these two medicines together as prescribed by your doctor. It is common for these drugs to be prescribed together for conditions like atrial fibrillation. Always ensure your doctor knows all the medications you are taking, and do not stop taking either medicine without medical advice.
Continue reading below
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
Patient picks for Drug interactions

Treatment and medication
Can I take Evana heavy period relief and Mefenamic acid together?
Taking these two medicines together significantly increases your risk of serious stomach problems, such as stomach ulcers, bleeding, or irritation of the stomach lining. It can also put extra strain on your kidneys.

Treatment and medication
Can I take Ibuprofen and Naproxen together?
Taking ibuprofen and naproxen together significantly increases your risk of serious side effects, particularly stomach ulcers, internal bleeding, and kidney problems. It can also make your blood pressure rise and cause fluid retention.
Continue reading below
Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published

Ask, share, connect.
Browse discussions, ask questions, and share experiences across hundreds of health topics.

Feeling unwell?
Assess your symptoms online for free
Sign up to the Patient newsletter
Your weekly dose of clear, trustworthy health advice - written to help you feel informed, confident and in control.
By subscribing you accept our Privacy Policy. You can unsubscribe at any time. We never sell your data.