Can I take Amlopadine and Nustendi together?
Drug interaction guide
Originally published 25 Jan 2026
Meets Patient’s editorial guidelines
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Taking amlodipine and Nustendi together can increase the amount of one of the ingredients in Nustendi (bempedoic acid) in your bloodstream. This may increase the risk of side effects from Nustendi, such as high levels of uric acid in the blood (which can cause gout) or, in rare cases, tendon problems.
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Why this happens
Amlodipine can slightly interfere with the way the body processes bempedoic acid (a component of Nustendi), leading to higher levels of the medication staying in your system for longer.
What you should do
It is generally safe to take these together, but your doctor should be aware. They may want to monitor your uric acid levels more closely or check for any signs of muscle or tendon pain. If you experience any unusual joint pain or swelling, contact your doctor.
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Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
25 Jan 2026 | Originally published
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